9309. Bartonella henselae, IgM antibodies (method IFT)

The test is elaborated to detect antibodies of the IgM class to Bartonella henselae – the cause of cat fever. The presence of IgM indicates a gastrointestinal tract or recent infection. The investigation was carried out using the indirect immunofluorescence (IFT) method, which ensures high sensitivity and specificity for the serological diagnosis of Bartonellosis.

Bartonella henselae is a gram-negative bacterium and the primary causative agent of cat scratch disease, which is transmitted to humans through contact with infected cats (bites, scratches, or damaged mucous membranes). The disease is typically characterized by localized inflammation of the lymph nodes, mild fever, rash, and pain at the site of injury.

IgM antibodies appear in the early stages of infection – usually within the first 1-2 weeks after infection – and persist for several weeks, allowing for the detection of an active or recent infection.

• If cat scratch disease is suspected, especially after contact with cats, with subsequent development of lymphadenitis, fever, or local inflammation.
• In patients with neurological or systemic symptoms of unknown etiology due to immunodeficiency (HIV/AIDS, chemotherapy).
• In cases of prolonged or slowly progressing fever, especially in children or young adults.
• For the differential diagnosis of infectious mononucleosis, toxoplasmosis, lymphomas, and in the presence of generalized or regional lymphadenitis.

• Venous blood

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules: