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  3. 9173. Islet cell antibody, IgG antibodies (ICA, method IFT)

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9173. Islet cell antibody, IgG antibodies (ICA, method IFT)

9173. Islet cell antibody, IgG antibodies (ICA, method IFT)

Turnaround time (days): 1

1490 ₴

Description

The pancreatic islet apparatus (islets of Langerhans) is the part of the pancreas responsible for the synthesis and secretion of insulin. The presence of antibodies to the islets of Langerhans may indicate the development of type 1 diabetes in a patient.

Detection of these antibodies is used not only for diagnosis but also to predict the likelihood of developing the disease. Crucially, this test can predict the development of diabetes 1-8 years before the onset of clinical symptoms.

These are antibodies to pancreatic β-cells (antigens contained in the cytoplasm of the islets of Langerhans). ICAs have significant prognostic significance in the development of type 1 diabetes. They appear 1-8 years before the clinical manifestation of the disease.

ICA are detected in 70-80% of patients with newly diagnosed type 1 diabetes compared to the non-diabetic control population. In at-risk individuals who have antibodies (autoantibodies to islet cells (ICA), insulin (IAA), glutamic acid decarboxylase (GADA), and tyrosine phosphatase (IA-2)) to two or more antigens, diabetes develops within 7-14 years.

When and who needs the test?

  • Differential diagnosis of type 1 and type 2 diabetes.
  • Identification of predisposition to diabetes in relatives of patients with type 1 diabetes.
  • Assessing the risk of developing diabetes in patients with polyendocrinopathy and other autoimmune diseases.

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach.
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

9173. Islet cell antibody, IgG antibodies (ICA, method IFT)

1490 ₴

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