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  2. 9035. Chromogranin A

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9035. Chromogranin A

9035. Chromogranin A

Turnaround time (days): 14

3860 ₴

Important information

*The test is performed at Synevo laboratory in Germany

Description

Chromogranin A is a protein synthesized by neuroendocrine cells. Its levels increase in the presence of neuroendocrine tumors (insulinoma, gastrinoma, carcinoid). The test is used to monitor treatment effectiveness, relapses, and prognosis.

Chromogranin A (CgA) is a glycoprotein produced by the secretory granules of neuroendocrine cells. It is involved in the storage, packaging, and release of hormones and neuropeptides. Elevated blood CgA levels are a marker of neuroendocrine activity and the presence of tumors.

The test's sensitivity and specificity are approximately 80%. It is not suitable for screening in the general population. Its level correlates with disease stage and survival prognosis for some tumor types.

Chromogranin A is a universal marker for most neuroendocrine tumors (NETs), regardless of location, including:

  • gastrointestinal tract;
  • pancreas;
  • bronchopulmonary system;
  • adrenal glands (pheochromocytoma);
  • pituitary gland.

When and who needs the test?

Indications for this test:

  • diagnosis of neuroendocrine tumors:
    • insulinoma;
    • gastrinoma;
    • carcinoid syndrome;
    • glucagonoma;
    • somatostatinoma;
    • growth hormone-releasing hormone-secreting tumors;
  • prostate cancer:
    • determination of tumor neuroendocrine activity;
    • evaluation of the effectiveness of hormone therapy;
    • prognostic factor in castration-resistant disease;
    • monitoring treatment and detection of recurrence of neuroendocrine tumors.

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach;
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

9035. Chromogranin A

3860 ₴

Information service

0 800 60 55 00

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