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  1. Home
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  3. Cardiovascular disease markers
  4. 9003. Homocysteine

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9003. Homocysteine

9003. Homocysteine

Turnaround time (days): 1

780 ₴

Description

Homocysteine is an amino acid produced in the body during methionine metabolism.

The homocysteine test may be used to:

  • diagnose vitamin B12 and/or folic acid deficiency;
  • screen individuals at high risk of heart attack or stroke.

Homocysteine is an amino acid produced in the body during methionine metabolism. It has a pronounced toxic effect on cells.

Under normal conditions, excess homocysteine is broken down with the involvement of folic acid and vitamins B12 and B6. The conversion of excess homocysteine back to methionine requires the active form of folic acid. The oxidation of homocysteine results in the formation of large amounts of free radicals, leading to endothelial cell damage, oxidation of low-density lipoproteins (LDL), and the development of cardiovascular disease.

Elevated homocysteine levels are an independent risk factor for the development of atherosclerosis, thrombosis, and osteoporosis.

Homocysteine levels are also influenced by lifestyle factors, including smoking and excessive alcohol and coffee consumption, as well as by genetic factors. Vegetarianism contributes to lower homocysteine levels.

When and who needs the test?

  • To assess the risk of developing atherosclerotic cardiovascular disease (atherosclerotic changes and the risk of thrombosis).
  • In the presence of significant atherosclerotic vascular changes despite normal lipid metabolism parameters.
  • For the management of patients with cardiovascular diseases (acute heart failure, chronic heart failure, coronary artery disease, myocardial infarction, stroke, cerebrovascular disorders, arterial hypertension, etc.).
  • For the management of patients with thrombotic disorders (pulmonary embolism and thrombosis).
  • As part of the evaluation of women with recurrent pregnancy loss (pregnancy loss at any stage of gestation), preeclampsia/eclampsia, and premature placental abruption.
  • As part of the evaluation of patients with hypothyroidism and diabetes mellitus.
  • For patients with any identified markers of thrombophilia.
  • For patients who have undergone gastric surgery.

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach;
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

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9003. Homocysteine

780 ₴

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