3387. Package No.22 (PCR: Mycoplasma hominis, Ureaplasma species, Chlamydia trachomatis, Trichomonas vaginalis (urogenital swab). Bacterial culture. Urogenital complex)

This is a comprehensive microbiological investigation combining PCR diagnostics for sexually transmitted infections (STIs) with bacteriological culture of urogenital specimens.

The panel allows detection of both specific pathogens (Chlamydia, Mycoplasma, Ureaplasma, Trichomonas) and opportunistic bacterial microflora.

Automated identification of microorganisms is performed using MALDI-TOF mass spectrometry on the MALDI Biotyper sirius IVD System analyzer (Bruker, Germany). If pathogens are detected, an antibiogram with MIC (minimum inhibitory concentration) determination is performed to assess antibiotic effectiveness and support selection of targeted therapy.

Package №22 is a comprehensive laboratory test aimed at a complete assessment of infectious and inflammatory processes of the urogenital tract.

It combines two diagnostic methods:

• PCR (polymerase chain reaction) – a highly sensitive molecular method that detects pathogen DNA at early stages, even in asymptomatic cases;
• bacteriological culture (culture test) – a method that allows evaluation of the composition of opportunistic microflora and determination of antibiotic susceptibility.

This combination provides the most complete picture of the urogenital microbiocenosis and enables the physician to prescribe individualized and effective treatment.

The test includes detection of the DNA of the following main pathogens:

• Chlamydia trachomatis – the most common etiological agent of nongonococcal urethritis, cervicitis, salpingitis, and prostatitis;
• Mycoplasma hominis – an opportunistic bacterium associated with bacterial vaginosis, urethritis, and pelvic inflammatory diseases;
• Ureaplasma species (U. parvum, U. urealyticum) – pathogens of urethritis, cervicitis, prostatitis, and pregnancy complications;
• Trichomonas vaginalis – a parasite causing trichomoniasis, which often presents asymptomatically in men.

Bacteriological culture of urogenital material additionally allows:

• determination of the qualitative and quantitative composition of the microflora;
• detection of other opportunistic bacteria (including Enterococcus spp., Escherichia coli, Klebsiella spp., Staphylococcus spp., Streptococcus spp., etc.);
• performing an antibiotic susceptibility test with MIC determination (excluding Gardnerella spp.).

Interpretation of culture results is carried out according to EUCAST and CLSI standards.

If pathogens are detected, self-medication is unacceptable – the results must be evaluated by a physician to select targeted therapy.

• In the presence of urogenital infection symptoms (discharge, itching, burning, pain during urination, pelvic discomfort).
• In cases of infertility (in men and women), before planning pregnancy or IVF.
• In cases of recurrent miscarriage.
• For follow-up after treatment of STIs.
• To clarify the etiology of inflammatory diseases (urethritis, vaginitis, prostatitis, cervicitis).
• After contact with an infected partner.

• Various types of biological material depending on the test
• Scrapes from various sites depending on the test