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  4. 3076. Package # 191 (PCR. Genetics. Thrombophilia)

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3076. Package # 191 (PCR. Genetics. Thrombophilia)

3076. Package # 191 (PCR. Genetics. Thrombophilia)

Number of tests: 8
PCR. Thrombophilia. SERPINE-1 gene, PAI-1 (675 5G>4G)
PCR. Thrombophilia. ITGB3-β-integrin gene (1565 T>C)

Turnaround time (days): 3

8640 ₴

Description

A comprehensive genetic test that identifies an inherited predisposition to blood clotting disorders. It is used to assess the risk of thrombosis, thromboembolism, pregnancy complications, myocardial infarction, stroke, and bleeding.

The hemostatic system maintains a balance between clot formation (to stop bleeding) and clot breakdown (to prevent excessive coagulation). Disruption of this balance caused by genetic mutations in specific factors leads to thrombophilia—a predisposition to increased clot formation or, less frequently, to bleeding disorders.

The panel includes key genes responsible for:

  • activation of the coagulation cascade (F2, F5, F7, F13A1);
  • platelet structure and function (GP1BA, ITGB3);
  • fibrin clot formation (FGB);
  • inhibition of fibrinolysis (SERPIN1 / PAI-1).

When and who needs the test?

  • Pregnancy planning and IVF.
  • Pregnancy loss (recurrent pregnancy loss, missed miscarriage, fetoplacental insufficiency).
  • A personal or family history of thrombosis, pulmonary embolism (PE), or stroke.
  • Severe preeclampsia, fetal growth restriction, or placental abruption.
  • Use of oral contraceptives or initiation of hormone replacement therapy (HRT).
  • Preparation for surgical procedures (especially gynecological, orthopedic, or oncological procedures).
  • Predicting the risk of postoperative complications (thrombosis, bleeding).
  • Screening of relatives of patients with an identified mutation.

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach;
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

3076. Package # 191 (PCR. Genetics. Thrombophilia)

8640 ₴

Information service

0 800 60 55 00

Free from mobile and stationary operators in Ukraine (except for the temporarily occupied territories)

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