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  2. 2381. Lactoferrin (stool)

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2381. Lactoferrin (stool)

2381. Lactoferrin (stool)

Turnaround time (days): 4

2175 ₴

Description

A fecal lactoferrin test is a noninvasive laboratory test that can detect intestinal inflammation. Lactoferrin is a protein found in neutrophil granules, so its elevated levels indicate the migration of immune cells to the intestinal mucosa in response to inflammation. Consequently, fecal lactoferrin, along with calprotectin, is a marker of gastrointestinal inflammation.

It is best to perform this test in conjunction with a stool analysis and a fecal occult blood test.

Lactoferrin is an iron-binding protein of the transferrin family, which possesses potent antibacterial, antiviral, anti-inflammatory, and immunomodulatory properties. In a healthy intestine, fecal lactoferrin levels are minimal or undetectable.

In inflammatory bowel diseases (IBD), such as Crohn's disease or ulcerative colitis, neutrophils intensively infiltrate the intestinal mucosa and lumen. This leads to a significant increase in fecal lactoferrin concentrations. Unlike functional disorders such as irritable bowel syndrome (IBS), IBD is organic in nature, and lactoferrin serves as one of the distinguishing markers between these conditions. Fecal lactoferrin is also a marker for bacterial inflammatory diarrhea in patients, such as those caused by Shigella, Salmonella, Campylobacter, and Clostridium difficile.

Lactoferrin testing is recommended as an alternative or adjunct to invasive colonoscopy, especially during follow-up of patients or during initial screening.

When and who needs the test?

When?

  • If you have symptoms of long-term inflammatory bowel disease (pain, diarrhea, mucus or blood in the stool, weight loss).
  • Before a colonoscopy as a preliminary screening.
  • To assess the activity of chronic inflammatory bowel disease.
  • To monitor the effectiveness of IBD treatment.

Who should use it?

  • Patients with suspected inflammatory bowel disease.
  • Patients with long-term gastrointestinal symptoms that are refractory to treatment.
  • Children and adults who need to avoid invasive diagnostic tests.
  • Patients with diagnosed IBD – to monitor disease activity and response to therapy.

Biological material

  • Stool

Preparing for stool testing

  • Feces should not be sent for testing after an enema, insertion of suppositories, or intake of castor or vaseline oil.
  • According to the indications, the doctor prescribes a trial diet, which the patient follows for 4-5 days.
  • Feces for testing should not contain any foreign impurities, such as urine.
  • For...

2381. Lactoferrin (stool)

2175 ₴

Information service

0 800 60 55 00

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