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2378. Quantiferon Test. Latent tuberculosis infection (plasma)
Description
The QuantiFERON test (IGRA, interferon-gamma release assay) is a modern laboratory blood test that detects the immune response to Mycobacterium tuberculosis. The test is used to diagnose latent tuberculosis infection (LTBI). A positive QuantiFERON test result indicates a high probability of tuberculosis.
When and who needs the test?
- Individuals with suspected latent tuberculosis infection, especially children and immunocompromised patients.
- Individuals in close contact with a person with active tuberculosis.
- To confirm skin test results and rule out a post-vaccination reaction in case of a positive Mantoux test (especially in children).
- Individuals with contraindications to tuberculin skin testing.
- HIV-positive patients, individuals on hemodialysis.
- Before prescribing immunosuppressive therapy (e.g., anti-TNF-based drugs: infliximab, adalimumab, etanercept), when latent tuberculosis must be ruled out.
- For screening of designated population groups (medical professionals, social workers, teachers, public transportation workers, etc.).
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach;
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...
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