2257. Ureaplasma urealyticum, IgM antibodies

IgM antibodies to Ureaplasma urealyticum indicate the primary or acute phase of infection. The test is used for the early diagnosis of urethritis, cervicitis, pregnancy complications, and when a recent infection is suspected.

Ureaplasma urealyticum is an opportunistic bacterium that, under certain conditions (such as weakened immunity, altered microflora, or sexually transmitted infection), can cause acute inflammatory diseases of the genitourinary system. In women, these may include cervicitis, vaginitis, endometritis, salpingitis, implantation failure, chorioamnionitis, and preterm labor. In men, these may include urethritis, acute prostatitis, and epididymitis.

IgM antibodies are markers of the primary immune response that appear early in infection. Their appearance indicates an acute or recent infection and allows for the diagnosis of ureaplasmosis before the appearance of IgG or when PCR results are still negative (at an early stage).

IgM testing is especially useful in the presence of:

• nonspecific symptoms of urethritis/cervicitis;
• suspected recent infection;
• acute urogenital infection in a partner;
• early complications of pregnancy.

• For symptoms of acute urethritis, cervicitis, or vaginitis.
• Couples with recent unprotected intercourse and suspected STIs.
• Women at risk of early pregnancy loss or during preparation for IVF.
• Men with acute prostatitis, pain, or dysuria.
• As part of a comprehensive examination for urogenital infections in the acute phase.

• Venous blood

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules: