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  3. Antiphospholipid syndrome
  4. 2116. Phosphatidylserine, IgG antibodies

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2116. Phosphatidylserine, IgG antibodies

2116. Phosphatidylserine, IgG antibodies

Turnaround time (days): 2

1290 ₴

Description

Phosphatidylserine is a negatively charged phospholipid that is a component of cell membranes.

Testing for IgG antibodies to phosphatidylserine is performed in the presence of venous thrombosis, pulmonary hypertension, migraines, seizures, and psychiatric disorders. Elevated levels of these antibodies indicate a chronic course or a previously experienced disease.

It is recommended to confirm the diagnosis of antiphospholipid syndrome and to identify the causes of thrombotic complications.
Prior to this test, testing for anti-beta-2-glycoprotein I antibodies, anticardiolipin antibodies, lupus anticoagulant, complete blood count, blood chemistry panel, and coagulation profile is recommended.

Phosphatidylserine is one of the negatively charged phospholipids that are components of cell membranes. Antibodies to phosphatidylserine are a type of antiphospholipid antibodies. They are considered one of the possible causes of antiphospholipid syndrome.

Antiphospholipid antibodies (aPL) are autoimmune antibodies, or IgG autoantibodies, directed against the main components of cell membranes—phospholipids—and, consequently, against the body's own cells and tissues.

Antibodies to phospholipids of vascular endothelial cells disrupt the balance between the coagulation and anticoagulation systems, shifting it toward thrombus formation.

When and who needs the test?

In combination with other tests for the diagnosis of antiphospholipid syndrome (unexplained thrombosis, infertility and recurrent pregnancy loss, thrombocytopenia).

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach;
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

2116. Phosphatidylserine, IgG antibodies

1290 ₴

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