2080. Cardiolipin, IgM antibodies

Cardiolipin is a phospholipid present in blood plasma and is part of the inner membrane of mitochondria.

Determination of IgM antibodies to it is carried out in the presence of venous thrombosis, pulmonary hypertension, migraine, seizures, mental disorders.

It is recommended for the diagnosis of antiphospholipid syndrome in the pathology of pregnancy, before taking oral contraceptives, for oncology, in case of a decrease in platelets and for assessing the risk of developing thrombosis.

The complex prescribes a coagulogram, antibodies to beta-2-glycoprotein1, a complete blood count.

Exclusion of APS as one of the forms of thrombophilia (especially at a young age) for:

• venous/arterial thrombosis (deep vein thrombosis, myocardial infarction, stroke, pulmonary embolism, visceral infarction, livedo reticularis, leg ulcers, transient cerebrovascular accident, etc.)
• miscarriage, fetal loss syndrome at different times, infertility, bleeding during pregnancy, development of pre- and eclampsia, placental insufficiency with fetal IUGR, premature placental abruption (PVNRP), stillbirths
• before taking OK, HRT and control when taking these drugs
• in cardiovascular pathology to assess the risk of developing or causing thrombotic complications (stroke, heart attack)
• with autoimmune diseases,any oncopathology, in case of detection of APTT elongation in the coagulogram
• negative results of other laboratory markers of APS,HELLP syndrome
• in case of positive Wassermann reaction (RW)thrombocytopenia, hemolytic anemia.

Retesting after a positive primary result to establish a diagnosis (after 12 weeks).

• Venous blood

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules: