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2050. Antisperm antibodies
Description
Antisperm antibodies are immunoglobulins that affect the sperm membrane, resulting in an inability to achieve fertilization. Antisperm antibodies may reduce sperm motility, prevent sperm from entering the cervical mucus, interfere with fertilization of the egg or blastocyst implantation, or inhibit embryo development. Antisperm antibodies may develop in both men and women.
This test is performed to diagnose infertility. It may be ordered together with testing for antibodies to ovarian tissue in women or a MAR test.
When and who needs the test?
- Infertility in a couple (testing is recommended for both the man and the woman, as antisperm antibodies may be present in either partner).
- Failed IVF attempts.
In men:
- abnormalities in semen analysis: agglutination, aggregation, reduced sperm motility, previous testicular trauma or biopsy, vasectomy;
- abnormal postcoital test.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach;
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...