1573. Package # 131 (Primary screening for hepatitis B)

A comprehensive diagnostic test for viral hepatitis B.

Hepatitis B surface antigen (HBsAg) is a protein found on the surface of the hepatitis B virus. HBsAg is detected in the blood during acute and chronic HBV infection, as well as in cases of recent vaccination.

Total antibodies to HBV core antigen (HBcorAg) can be detected in cases of acute and chronic HBV infection, and may also indicate a past infection.

This combined testing differentiates HBV infection from the post-vaccination immune response.

Important! Antibodies to HBV core antigen are not detected in vaccinated individuals.

Viral hepatitis B is an infectious disease that affects the liver. Infection can occur through contact with infected blood (blood transfusions, hemodialysis, injection drug use, etc.), sexual intercourse, and mother-to-child transmission during childbirth.

The disease is characterized by the following symptoms:

• general weakness, fever, loss of appetite, nausea/vomiting lasting several days;
• yellowing of the skin and whites of the eyes;
• dark urine and discolored stool.

A distinction is made between acute and chronic HBV infection.

Chronic infection can lead to the development of cirrhosis and liver cancer (hepatocellular carcinoma).

• If the following symptoms are present: yellowing of the mucous membranes and skin, pain in the right upper quadrant, dark urine, discolored stool, vomiting.
• To confirm the diagnosis of acute hepatitis B.
• To confirm the diagnosis of chronic hepatitis B (if the result is positive for more than 6 months).
• Prenatal screening of children born to mothers who are HBV carriers to determine prophylactic treatment.
• Monitoring the treatment of chronic HBV.
• Preventive screening of risk groups and donors.
• Decision-making about hepatitis B vaccination.
• In preparation for pregnancy and during pregnancy.

• Venous blood

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules: