9761. Genetics. Rhesus factor of the fetus in the mother's blood (RHD gene)
Turnaround time (days): 11
4140 ₴
Description
Genotyping for the presence or absence of the RHD gene. Fetal DNA isolated from the mother's blood is used as material for research.
Genotyping is performed on several fragments (7th and 10th exons) of the gene.
A necessary condition is its use during 10 and more weeks of pregnancy in serologically Rh-negative women.
The main method of genotyping is the polymerase chain reaction, which detects the presence or absence of the RHD gene in the material.
Indications for use:
- Detection of the presence/absence of the 7th and 10th exons of the RHD gene.
An test to determine the Rh factor of the fetus in fetal DNA, which is recommended from the 10th week of pregnancy for Rh-negative pregnant women. Obtaining a reliable result may be affected by the presence of a serological false-negative result in the mother (Rh in the presence of the RHD gene) due to the presence of mutations within the RHD gene or changes in its expression.
When and who needs the test?
- Detection of the presence/absence of the 7th and 10th exons of the RHD gene.
An test to determine the Rh factor of the fetus in fetal DNA, which is recommended from the 10th week of pregnancy for Rh-negative pregnant women. Obtaining a reliable result may be affected by the presence of a serological false-negative result in the mother (Rh in the presence of the RHD gene) due to the presence of mutations within the RHD gene or changes in its expression.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...