9463. Aquaporin-4, IgG antibodies (method IFT)
Important information
*The test is performed at Synevo laboratory in Germany
Description
Antibodies to aquoporin-4 are the main serological marker of Devic's neuromyelitis optica. It is an autoimmune demyelinating disease that causes damage to the optic nerves (neuritis) and spinal cord (myelitis) and is manifested by visual impairment, muscle weakness, decreased sensation, involuntary urination and defecation.
The analysis is necessary for the differential diagnosis of multiple sclerosis and neuromyelitis optica.
Additionally, tests for the presence of antinuclear antibodies and other indicators of demyelinating diseases are prescribed.
When and who needs the test?
- diagnosis of opticomyelitis neuromyelitis optica spectrum disorder (Devic’s disease), recurrent transverse myelitis and recurrent optic neuritis;
- differential diagnosis of neuromyelitis optica spectrum disorder and multiple sclerosis;
- monitoring of the course of neuromyelitis optica spectrum disorder;
- assessment of the effectiveness of therapy.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...