9305. Proinsulin
Description
Proinsulin is the precursor and the main depot of insulin in the human body. Proinsulin levels demonstrate functional activity of pancreatic β-cells.
Determination of proinsulin levels is used to diagnose insulinoma (a tumor of the pancreas that actively synthesizes proinsulin) and RS ⅓ convertase deficiency, to determine the cause of hypoglycemia, and to assess the state of the pancreas.
To increase the information content, it is better to take this test in conjunction with the assessment of insulin or C-peptide levels.
When and who needs the test?
- diagnostics of hypoglycemic conditions;
- suspected insulinoma;
- assessment of the functional state of β-cells of the pancreas;
- suspected deficiency of PC 1/3 convertase.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...