9220. Proteinase 3 (PR3), IgG antibodies
Description
Proteinase 3 is a cytoplasmic protein of neutrophils, monocytes, and vascular wall cells, to which antibodies are formed in autoimmune vascular lesions (vasculitis), primarily Wegener's granulomatosis.
If there are the following symptoms: weakness, fever, pain in the joints and muscles, vasculitis, scleritis, damage to the respiratory system, kidneys, the test is used for the diagnosis and differential diagnosis of systemic vasculitis, Wegener's granulomatosis, disease monitoring.
In the complex, it is possible to prescribe a test for blood pressure to myeloperoxidase, tests for the determination of rheumatoid factor, C-reactive protein.
When and who needs the test?
- early diagnosis and differential diagnosis of systemic vasculitis;
- diagnosis of limited (nasopharyngeal) and systemic forms of Wegener’s granulomatosis;
- monitoring of the activity of Wegener’s granulomatosis;
- diagnosis of rapidly progressive glomerulonephritis and acute renal failure;
- differential diagnosis.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...
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