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  2. 9197. β2-microglobulin

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9197. β2-microglobulin

9197. β2-microglobulin

Turnaround time (days): 1

470 ₴

Description

β2-Microglobulin is a universal marker used to assess kidney function, the activity of autoimmune diseases, and monitor the treatment of hematologic malignancies. It is also used after kidney transplantation.

β2-Microglobulin is a low-molecular-weight protein synthesized by all nucleated cells. It is a component of MHC class I (histocompatibility antigens) and reflects the activity of cellular immunity.

Its concentration increases in:

  • oncohematological diseases – multiple myeloma, B-cell lymphomas, chronic lymphocytic leukemia;
  • decreased kidney function – especially in patients after transplantation, during dialysis, or in the presence of drug-induced nephrotoxicity;
  • systemic diseases – such as rheumatoid arthritis, systemic lupus erythematosus (SLE), and scleroderma.

It is used for:

  • assessing disease activity, predicting survival and risk of relapse in oncology;
  • monitoring graft rejection or kidney transplant function;
  • diagnosing the type of nephron damage – tubular or glomerular;
  • assessing the effectiveness of hemodialysis (levels before/after the procedure);
  • monitoring drug toxicity.

When and who needs the test?

In oncology:

  • patients with multiple myeloma, B-lymphomas, and CLL;
  • to assess response to therapy, prognosis, and staging.

In nephrology:

  • patients after kidney transplantation;
  • if drug nephrotoxicity is suspected;
  • in systemic diseases with kidney damage.

Other cases:

  • HIV infection – as a marker of kidney progression;
  • systemic autoimmune diseases – to monitor kidney activity and function.

Recommended in combination with tumor markers (LDH, CEA, β-hCG), clinical and biochemical blood tests.

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach;
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

9197. β2-microglobulin

470 ₴

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