9196. Glutamic acid decarboxylase (GADA), IgG antibodies
Description
Glutamic acid decarboxylase is one of the targets in the islet cells of Langerhans for antibodies synthesized by the immune system.
Detection of antibodies to glutamic acid decarboxylase allows one to identify individuals at increased risk of developing type 1 diabetes or those requiring insulin treatment, and to differentiate between different types of diabetes.
This test should be performed in conjunction with detection of antibodies to other pancreatic autoantigens, as well as genetic and metabolic markers of diabetes.
When and who needs the test?
- Diagnosis of type 1 diabetes mellitus.
- Differential diagnosis of type 1 and type 2 diabetes mellitus.
- Prediction of the risk of developing type 1 diabetes mellitus in overweight individuals, those with impaired carbohydrate tolerance, and in women with gestational diabetes mellitus.
- Diagnosis and prediction of the development of type 1 diabetes mellitus in close relatives of patients with diabetes.
- Screening of healthy relatives of patients with diabetes who wish to donate kidneys or partial pancreas.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...
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