9172. Insulin, IgG antibodies (quantification)
Description
Insulin antibodies are produced by the human immune system that selectively attack and damage (deactivate) insulin. Normally, they are absent or present in minimal quantities. Elevated levels of insulin antibodies are one of the causes of type 1 diabetes.
Determining insulin antibody levels is used to differentiate between different types of diabetes, determine the risk of developing type 1 diabetes, and assess the adequacy of diabetes treatment with animal-based insulins.
When and who needs the test?
- Differential diagnosis of type 1 diabetes and type 2 diabetes.
- Prognosis of type 1 diabetes in asymptomatic individuals with a positive family history, the presence of certain HLA alleles, and other specific antibodies (islet cell autoantibodies (ICA), glutamine alkyl decarboxylase (GADA), tyrosine phosphatase (IA-2), and zinc transporter 8 (ZnT8)).
- Diagnosis of the causes of hypoglycemia in individuals without diabetes.
- Assessment of insulin resistance in patients diagnosed with type 1 diabetes and diabetes.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...