2517. Package # 306.1 (Catecholamines: adrenaline, norepinephrine, dopamine (daily urine))

This package is elaborated to diagnose tumors associated with abnormal catecholamine levels, such as pheochromocytoma and paraganglioma. Catecholamines are a group of similar hormones produced by the adrenal medulla in response to stress. The main catecholamines – dopamine, epinephrine, and norepinephrine – regulate heart rate, blood pressure, and energy metabolism. After their action, catecholamines are metabolized and excreted primarily in the urine as metabolites. A 24-hour urine sample allows for the determination of the total amount of catecholamines produced over the course of a day, which more accurately reflects metabolic activity than a blood sample. Urine levels are less susceptible to the effects of acute stressors or temporary physiological changes that can affect plasma levels. This stability allows for a more accurate interpretation of the results.

Catecholaminess are a group of similar hormone produced by the adrenal medulla. The main catecholamines are dopamine, adrenaline (epinephrine), and norepinephrine. They are released into the bloodstream in response to physical or emotional stress and participate in the transmission of nerve impulses to the brain, promote the release of glucose and fatty acids as an energy source, and dilate the bronchioles and pupils. Norepinephrine constricts blood vessels, increasing blood pressure, while adrenaline increases heart rate and stimulates metabolism. After completing their action, these hormones are broken down into physiologically inactive substances (homovanillic acid, normetanephrine, etc.). Both the hormones themselves and their metabolites are excreted in the urine.

• Diagnosis of chromaffin tumors in patients with corresponding symptoms.
• Monitoring the effectiveness of chromaffin tumor treatment, particularly after its removal, to ensure there is no recurrence.

• Urine

COLLECTION RULES