2506. Package # 43.2 (Screening for antiphospholipid syndrome)
Number of tests: 5
β-2-glycoprotein I, IgG antibodies
β-2-glycoprotein I, IgM antibodies
Turnaround time (days): 1
2420 ₴
Description
A comprehensive laboratory test necessary for the diagnosis of autoimmune diseases, primarily antiphospholipid syndrome. In the case of such a disease, the body begins to produce antibodies against phospholipids – important chemical compounds.
Antiphospholipid antibodies (APAs) are a heterogeneous group of autoantibodies directed against proteins associated with membrane phospholipids.
The AFA group includes:
- anticardiolipin antibodies (ACA);
- antibodies to beta-2-glycoprotein;
- lupus anticoagulant.
The APA test is used both for the direct diagnosis of APS and for assessing the risk of thrombosis. Different types of APA have different thrombogenic potential. In addition, the risk of thrombosis also depends on the combination of APA: the presence of three main types of APA (APA, lupus anticoagulant and antibodies to beta-2-glycoprotein), the so-called triple seropositivity is associated with a higher risk of thrombosis.
When and who needs the test?
The study is carried out as part of the diagnosis of obstetric pathology and the search for the causes of sudden thrombosis.
Obstetric:
- Unexplained fetal death or missed abortion
- Recurrent pregnancy loss (3 or more spontaneous abortions)
- Unexplained fetal death in the 2nd or 3rd trimester
- Severe preeclampsia before 34 weeks of pregnancy
- Unexplained severe fetal growth restriction
Non-obstetric:
- Non-traumatic thrombosis or thromboembolism (venous and arterial)
- Stroke, especially in women 24-50 years old
- Unexplained transient cerebrovascular accidents
- Autoimmune thrombocytopenia
- Autoimmune hemolytic anemia
- False positive test for syphilis
- Manifestations of systemic lupus erythematosus or other autoimmune diseases.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...