2461. Allergen. Molecule. Hazelnut (rCor a1), IgE antibodies

Hazelnut allergy is one of the varieties of food allergy to nuts, in which the allergens are nuts of the hazel genus. Hazelnut allergy is more common in patients with allergies to tree pollen. The frequency and type of allergic reaction depend on the prevalence in a particular region of such trees as birch, alder, hazel and hornbeam. Allergens are present both in hazel pollen and in its fruits - homologues of Cor a 1, Cor a 2, Cor a 6.

Seven more allergens have been described exclusively in hazelnuts: LTP protein Cor a 8 and storage proteins Cor a 9, Cor a 11, Cor a 12, Cor a 13, Cor a 14, Cor a 15. All these proteins are resistant to high temperatures and digestion, therefore capable of causing true food allergies with severe reactions, including anaphylaxis. The breakdown products of these proteins are also hard to digest, penetrating through the gastrointestinal tract into the bloodstream, and are recognized by the immune system as hostile. Therefore, it secretes antibodies against such substances.

• recommended for suspected hazelnut allergy in children and adults;
• when examining patients with polysensitization;
• when examining children and adults with bronchial asthma, allergic rhinitis / conjunctivitis, atopic dermatitis, urticaria, angioedema, anaphylactic shock, redness and burning in the mouth, nausea, vomiting, diarrhea after eating hazelnuts.

• Venous blood

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules: