2455. Helicobacter pylori (protein CagA), IgG antibodies
Description
Helicobacter pylori (H. pylori) is a Gram-negative, spiral-shaped bacterium that can colonize the lining of the stomach and duodenum and cause inflammation.
Serological studies reveal specific immunoglobulins in the blood directed against H. pylori. H. pylori infection is accompanied by the development of a local and systemic immune response. Following a transient increase in the titer of class M immunoglobulins (IgM), a prolonged and significant increase in IgG, as well as IgA antibodies in the blood serum, follows. IgGs are found in 95-100% of H. pylori infections. The sensitivity of H. pylori serological tests in children is lower.
When and who needs the test?
- recommended for detection of H. pylori in patients with suspected gastritis, gastric or duodenal ulcer;
- for indirect assessment of the state of the gastric mucosa (serological biopsy) during treatment.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...