2307. Allergen. Molecule. Dog (rCan f2), IgE antibodies
Description
The allergen rCan f 2 belongs to the group of dog epidermal proteins, which enter the body primarily via the airborne route or through direct contact with the animal. Dog allergens are widely distributed in the environment and may be detected even in premises where no pets are kept. Symptoms of allergy to dog epidermal allergens may appear within minutes of exposure, gradually intensifying and reaching their peak over 3-4 hours. In sensitized individuals, reactions manifest as allergic rhinitis, conjunctivitis, urticaria, eczema, and pruritus; in patients with bronchial asthma, inhalation of allergens frequently provokes cough, dyspnoea, or bronchospasm. Determination of specific IgE antibodies to rCan f 2 is used to identify sensitization; however, this allergen is not an independent marker of dog allergy and requires interpretation in conjunction with other epidermal allergens.
When and who needs the test?
Recommended for determining dog allergen sensitivity:
- if sensitization to dogs is suspected;
- during examination of children and adults with bronchial asthma, allergic rhinitis/conjunctivitis, atopic dermatitis, urticaria, angioedema, gastrointestinal disorders, anaphylactic shock, and other manifestations of allergic diseases;
- if planning to get a dog in a family with children and adults prone to allergic reactions.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...
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