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  4. 2213. Lymphocytic profile of peripheral blood

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2213. Lymphocytic profile of peripheral blood

2213. Lymphocytic profile of peripheral blood

Turnaround time (days): 3

1740 ₴

Description

A peripheral blood lymphocyte profile is a laboratory test aimed at the relative composition of the main lymphocyte subpopulations. This test is crucial for assessing the immune system, diagnosing immunodeficiencies, autoimmune diseases, infectious diseases, and hematologic oncology, as well as for pre- and post-transplant evaluation. It should be performed in conjunction with clinical and biochemical blood tests.

The peripheral blood lymphocyte profile reflects the state of the cellular and humoral components of the immune system. Cellular immunity is represented by different populations of T and B lymphocytes, the ratio of which plays an important role in assessing the state of this component of the immune system.

The peripheral blood lymphocyte profile contains the following indicators:

  • CD3+/CD45+ – total T lymphocytes
    These are key cells of cellular immunity that recognize pathogens and regulate the activity of other immune cells.
  • CD3+CD4+/CD45+ – T helper cells
    Coordinate the immune response, activating B lymphocytes to synthesize antibodies.
  • CD3+CD8+/CD45+ – T suppressor cells
    Destroy virus-infected and tumor cells.
  • CD3+CD4+CD8+/CD45+ – T-cytotoxic lymphocytes
    This is a small population that usually appears in children and sometimes increases in the presence of autoimmune or viral diseases.
  • Immunoregulatory index (T-helper/T-suppressor cells)
    Represents the balance between helper and suppressor cells.
  • CD19+/CD45+ – B-lymphocytes
    Responsible for antibody synthesis and humoral immunity.
  • CD45+ – global leukocyte antigen
    This marker is found on the surface of all leukocytes. It is used as a baseline control for analyzing white blood cell populations.

This test allows:

  • to identify changes in the composition and functional activity of lymphocytes;
  • to assess the immune response to infections, tumors, or autoimmune processes;
  • detect immunoregulatory disorders at early stages.

This test has great diagnostic and prognostic value in immunology, hematology, oncology, and infectious medicine.

When and who needs the test?

  • To assess the immune system during frequent bacterial and viral infections.
  • In the presence of autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis).
  • To monitor immune status during and after chemotherapy and immunosuppressive therapy.
  • During the diagnosis and monitoring of hematological diseases (leukemia, lymphomas).
  • Patients with suspected immunodeficiencies, particularly HIV/AIDS.
  • Patients with hematological pathologies (leukemia, lymphomas).
  • Patients before and after transplantation to monitor immunosuppression.
  • Patients with suspected lymphoproliferative diseases.

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach;
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

2213. Lymphocytic profile of peripheral blood

1740 ₴

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