2142. Tick-borne encephalitis virus, IgG antibodies

The test detects the presence of IgG antibodies to the tick-borne encephalitis virus in the blood serum. The presence of IgG indicates a late-stage infection, a previous infection, or immunity developed after vaccination.

Tick-borne encephalitis virus (TBE) is an infectious disease transmitted by the bite of an infected tick. The infection is characterized by an acute course, including fever, intoxication syndrome, and severe central nervous system (CNS) damage. The incubation period for TBE is 7 to 14 days.

The first phase of TBE lasts 1-8 days and is characterized by nonspecific symptoms of intoxication – fever, headache, weakness, myalgia, joint pain, and sometimes nausea. This is followed by a respite of up to 7 days with a temporary improvement in health. In the second phase, meningoencephalitis develops, manifested by severe headache, fever, impaired consciousness, seizures, paresis, impaired coordination, and, in severe cases, coma.

Vaccination and tick bite prevention are the primary protective measures.

IgG testing is used to diagnose the disease, monitor immune status, and plan revaccination.

• Serological confirmation of clinical and epidemiological suspicions of viral tick-borne encephalitis.
• For differential diagnosis of central nervous system lesions (infectious meningitis and encephalitis of other origins, epilepsy, aseptic meningitis).
• For assessing post-vaccination immunity (4-6 weeks after vaccination or before scheduled revaccination).

• Venous blood

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules: