2117. Phosphatidylserine, IgM antibodies
Description
Phosphatidylserine is a negatively charged phospholipid that is part of cell membranes. Determination of IgM antibodies to it is carried out in the presence of venous thrombosis, pulmonary hypertension, migraine, seizures, mental disorders.
Recommended for the diagnosis of antiphospholipid syndrome with negative results of specific tests for APS and to identify the causes of thrombotic complications.
Before this test, tests are prescribed for antibodies to beta-2-glycoprotein 1, cardiolipin, lupus anticoagulant, coagulogram.
When and who needs the test?
Exclusion of APS as one of the forms of thrombophilia (especially at a young age) with:
- negative results of laboratory criteria for APS (VA, AKA and β-2-glycoprotein I);
- venous/arterial thrombosis (deep vein thrombosis, myocardial infarction, stroke, pulmonary embolism, visceral infarction, livedo reticularis, leg ulcers, transient cerebrovascular accident, etc.);
- miscarriage, fetal loss syndrome at different times, infertility, bleeding during pregnancy, development of pre- and eclampsia, placental insufficiency with fetal IUGR, premature placental abruption (PONRP), stillbirth;
- before starting OC, HRT and to control the intake of these drugs;
- autoimmune diseases;
- any oncopathology;
- thrombocytopenia, hemolytic anemia.
Retesting after a positive primary result at 12 weeks.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...