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  4. 2072. Epstein-Barr virus (early antigen, EA), IgG antibodies

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2072. Epstein-Barr virus (early antigen, EA), IgG antibodies

2072. Epstein-Barr virus (early antigen, EA), IgG antibodies

Turnaround time (days): 2

460 ₴

Description

EBV Early Antigen (EA) IgG antibodies appear at an early stage of infection and may indicate an acute phase, reactivation, or chronic course of EBV infection. They are used to clarify the phase of the disease alongside other markers (VCA, EBNA).

Epstein-Barr virus (EBV, herpesvirus type 4) is the causative agent of infectious mononucleosis and latent viral infections associated with the risk of chronicity, reactivation, and cancer. Following infection, the body produces a sequential immune response to several viral antigens, particularly early antigens (EA).

IgG antibodies to EA:

  • appear in the acute phase of infection (mainly in the first 2-3 weeks);
  • may disappear after recovery or persist for a long time in the case of chronic or reactivated EBV;
  • detection of EA-IgG in combination with other antibodies allows one to assess the activity of the infection.

Clinical significance:

  • EA-IgG (+) + VCA-IgM (+), EBNA (–) – characteristic of acute primary infection;
  • EA-IgG (+) + EBNA-IgG (+), IgM (–) – may indicate reactivation or chronic active EBV infection;
  • EA-IgG (–) in the presence of EBNA-IgG → past infection, no signs of activity.

When and who needs the test?

  • Patients with suspected infectious mononucleosis, to determine the active phase.
  • In cases of recurrent symptoms, prolonged low-grade fever, or lymphadenopathy.
  • In patients with immunodeficiency or lymphoproliferative disorders.
  • If viral reactivation is suspected, particularly in pregnant women, cancer patients, or after transplantation.
  • In combination with other EBV markers (VCA-IgM, VCA-IgG, EBNA-IgG) – for a complete assessment of the infection phase.

Biological material

  • Venous blood

Preparing for a blood test

In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:

  • an important condition for laboratory tests is to take blood on an empty stomach;
  • 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...

Cheaper in a package

2172. Package # 5.7 (Epstein-Barr virus, IgG antibodies)

Number of tests: 3
Epstein-Barr virus (early antigen, EA), IgG antibodies
Epstein-Barr virus (capsid antigen, VCA), IgG antibodies
Epstein-Barr virus (nuclear antigen, EBNA), IgG antibodies

Turnaround time (days): 2

1240 ₴

2072. Epstein-Barr virus (early antigen, EA), IgG antibodies

460 ₴

Information service

0 800 60 55 00

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