1627. Protein S (activity)
Important information
*The test is performed at Synevo laboratory in Germany
Description
Protein S level is to define content of physiological anticoagulant in the blood and is used in a comprehensive examination of patients with suspected thrombophilia.
When and who needs the test?
The test is elaborated to identify protein S deficiency, primarily of a hereditary nature. Despite the fact that the tactics of managing an acute thrombotic event do not depend on the identified hereditary protein S deficiency, its diagnosis is important for further preventive measures to minimize the risk of recurrent thrombosis.
Recommended for complex diagnostics of thrombophilia, in the presence of episodes of arterial or venous thrombosis, as well as thromboembolic complications that do not have any other obvious causes, especially if they occur in young people (under 50 years old), are familial, and also constantly recur. Determining the level of free protein S is also advisable in the complex diagnostics of the causes of thrombotic complications during pregnancy. An elevated level of free protein S is usually not associated with a medical problem and is considered clinically insignificant.
A decrease in free protein S is observed in congenital deficiency, liver diseases with impaired synthetic function, nephrotic syndrome, disseminated intravascular coagulation syndrome, some systemic diseases (lupus erythematosus), treatment with L-asparaginase, taking indirect anticoagulants (antagonists) (oral contraceptives), during pregnancy and the postpartum period.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...