1180. Protein C (activity)
Description
The test is aimed at determining protein C in the blood to diagnose possible causes of thrombosis and thrombotic complications.
When and who needs the test?
It is recommended to carry out treatment with indirect anticoagulants under the control of protein C activity. Control and repeated determinations of protein C should be carried out at least one month after drug withdrawal. Determination of the concentration or activity of protein C in the blood is important in the diagnosis of various pathological conditions and diseases. A decrease in these indicators may be associated with a violation of the synthesis of protein C, its rapid consumption or a violation of the protein structure and its functional inferiority.
Protein C synthesis can be reduced due to congenital insufficiency, vitamin K deficiency, liver pathology, impaired its synthetic function, in the neonatal period and in the elderly. Excessive protein consumption can be observed in thrombosis, thromboembolism, consumption coagulopathy, disseminated intravascular coagulation syndrome (DIC syndrome), after major operations and injuries.
Impaired functional activity of protein C can be observed when taking anticoagulant drugs, in particular, when taking warfarin orally. An increase in protein C concentration may be observed during pregnancy, when taking estrogen-based oral contraceptives, and in kidney disease.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...