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1169. Lupus anticoagulant
Description
Lupus anticoagulant is a laboratory test that detects autoantibodies capable of interfering with phospholipid-dependent blood coagulation processes. The test helps identify the risk of thrombosis associated with antiphospholipid syndrome or systemic lupus erythematosus. It is one of the main laboratory criteria for the diagnosis of antiphospholipid syndrome.
When and who needs the test?
Exclusion of APS as one of the forms of thrombophilia (especially at a young age):
- venous/arterial thrombosis (deep vein thrombosis, myocardial infarction, stroke, pulmonary embolism, visceral infarction, livedo reticularis, leg ulcers, transient cerebrovascular accidents, etc.)
- miscarriage, fetal loss syndrome at different periods, infertility, bleeding during pregnancy, development of pre- and eclampsia, placental insufficiency with IUGR of the fetus, premature placental abruption (PVNRP), stillbirth
- before you start taking OK, HRT and under control when taking these drugs
- in cardiovascular pathology to assess the risk of development or cause of thrombotic complications (stroke, heart attack)
- autoimmune diseases
- any oncopathology
- detection of APTT elongation in the coagulogram
- negative results for other laboratory markers of APS
- HELLP-syndrome
- positive Wasserman reaction (RW)
- thrombocytopenia, hemolytic anemia
Retesting after a positive primary result to establish a diagnosis (after 12 weeks)
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach;
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...
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