1105. PAPP-A (Pregnancy-Associated Plasma Protein A)
Important information
*The biomaterial can be taken during the whole working day of the lab center
*For woman an operator specifies the day of the menstrual cycle or the gestational age
Description
PAPP-A is a first-trimester screening test for detecting fetal chromosomal abnormalities. It is recommended for all pregnant women, especially if ultrasound findings suggest fetal abnormalities, to assess pregnancy progress and the risk of preeclampsia. It is most often performed in conjunction with free β-hCG testing.
When and who needs the test?
- All pregnant women in the first trimester (8-14 weeks of gestation) as part of standard prenatal screening.
- Women with high-risk factors:
- age over 35;
- history of pregnancy complications (miscarriages, fetal growth restriction, preeclampsia);
- family history of hereditary or chromosomal disorders;
- exposure to teratogenic factors (infections, radiation, medications) before or during early pregnancy.
- To predict preeclampsia – in combination with PLGF levels in women with appropriate clinical indications.
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...
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