1105. PAPP-A (Pregnancy-Associated Plasma Protein A)
Important information
*The biomaterial can be taken during the whole working day of the lab center
*For woman an operator specifies the day of the menstrual cycle or the gestational age
Description
The pregnancy-associated plasma protein A test is a screening test performed during the first trimester of pregnancy to detect fetal chromosomal abnormalities. It is recommended for all pregnant women who have signs of pathology on ultrasound to assess the progression of pregnancy and the development of eclampsia.
A decrease in the level of protein A in terms of 8-14 weeks may indicate Down syndrome, Edwards, Cornelia de Lange, the threat of miscarriage or intrauterine fetal death.
In the complex, an analysis is prescribed for free β-chorionic gonadotropin.
When and who needs the test?
- age over 35 years old;
- miscarriage and severe complications of pregnancy in the past;
- chromosomal abnormalities, Down's disease or congenital malformations during previous pregnancies;
- hereditary diseases in the familypast infections, radiation exposure, intake in early pregnancy or shortly before it;
- drugs that have a teratogenic effect (may cause birth defects and fetal anomalies);
- assessment of the risk of developing preeclampsia in pregnant women with risk factors (together with determining the level of PLGF).
Biological material
- Venous blood
Preparing for a blood test
In order to exclude factors that may affect the test results, we recommend to follow the preparation rules:
- an important condition for laboratory tests is to take blood on an empty stomach.
- 6-12 hours before the test, you should avoid eating, drinking alcohol, smoking, and limit physical activity. Drinking...
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